Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 8/20 | 1.00 |
| ▸ | ITPR2 | Q14571 | 4/20 | 1.00 |
| ▸ | ITPR1 | Q14643 | 4/20 | 1.00 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.84 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.75 |
| ▸ | AKT1 | P31749 | 1/20 | 0.75 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9091859 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL9093199 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL9094714 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL2510044 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL9091912 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL405897 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL8775574 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL2044892 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL9387601 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL15067019 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654779-A1 | LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF | Ludwig Institute for Cancer Research, Ltd. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088414-A1 | LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2012-06-28 | — | — | WO | disclosed |
| EP-0748210-A1 | METHODS OF USING CYCLIC POLYANIONIC POLYOL DERIVATIVES FOR REGULATING SKIN WRINKLES | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-18 | — | — | EP | disclosed |
| EP-0724445-A1 | THE USE OF INOSITOLTRISPHOSPHATE FOR THE PREPARING OF MEDICAMENTS | PERSTORP AB (SE) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995023588-A1 | METHODS OF USING CYCLIC POLYANIONIC POLYOL DERIVATIVES FOR REGULATING SKIN WRINKLES | THE PROCTER & GAMBLE COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |
| WO-1995010285-A1 | THE USE OF INOSITOLTRISPHOSPHATE FOR THE PREPARING OF MEDICAMENTS | PERSTORP AB (SE) | 1995-04-20 | — | — | WO | disclosed |
| EP-0579957-A1 | Preparation of isomers of myoinositol derivatives | 3i RESEARCH EXPLOITATION LIMITED (GB) | 1994-01-26 | — | — | EP | disclosed |
| EP-0376955-B1 | PREPARATION OF ISOMERS OF MYO-INOSITOL DERIVATIVES | 3I RES EXPL LTD (GB) | 1994-01-05 | — | — | EP | disclosed |
| EP-0536269-A1 | THE USE OF INOSITOLTRISPHOSPHATE FOR THE PREPARING OF MEDICAMENTS | PERSTORP AB (SE) | 1993-04-14 | — | — | EP | disclosed |
| US-5128332-A | Method of treating cardiovascular diseases using inositoltrisphosphate | PERSTORP AB (SE) | 1992-07-07 | — | — | US | disclosed |
| EP-0376955-A1 | PREPARATION OF ISOMERS OF MYO-INOSITOL DERIVATIVES. | 3I RES EXPLOIT LTD (GB) | 1990-07-11 | — | — | EP | disclosed |
| WO-1989000156-A1 | PREPARATION OF ISOMERS OF MYO-INOSITOL DERIVATIVES | 3I RESEARCH EXPLOITATION LIMITED (GB) | 1989-01-12 | — | — | WO | disclosed |