SCHEMBL27246717

SCHEMBL27246717

Clc1ccc2c(ccc3c(Cl)nccc32)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.65
LMNA P02545 1/20 0.65
CYP3A4 P08684 1/20 0.65
APEX1 P27695 1/20 0.65
MAPK1 P28482 1/20 0.65
PMP22 Q01453 1/20 0.65
NR4A2 P43354 4/20 0.42
SOS2 Q07890 1/20 0.42
CYP2A6 P11509 1/20 0.39
HIPK2 Q9H2X6 1/20 0.39
MAP4K4 O95819 1/20 0.38
POLB P06746 1/20 0.38
CYP1A2 P05177 1/20 0.38
TYMS P04818 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CCR1 P32246 1/20 0.36
PKM P14618 1/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30038739 1.00 MAPT (0.65) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL1258573 0.86 NR4A2 (0.46) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL29733493 0.86 NR4A2 (0.46) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL29228475 0.81 LMNA (0.61) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL30960545 0.81 LMNA (0.61) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL23557300 0.81 MAPT (0.61) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL22462704 0.81 MAPT (0.61) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL12205409 0.81 CYP2A6 (0.55) LMNACYP3A4NR4A2CYP2A6POLB
SCHEMBL6561368 0.78 CYP2A6 (0.57) LMNACYP3A4NR4A2CYP2A6POLB
SCHEMBL610880 0.78 CYP3A4 (1.00) MAPTLMNACYP3A4APEX1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255173-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-08-07 US disclosed
US-12324348-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-06-03 US disclosed
US-20240206317-A1 ORGANIC METAL COMPLEX AND ORGANIC LIGHT EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2024-06-20 US disclosed
US-20220352476-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-11-03 US disclosed
CN-113321686-A Organic electroluminescent material and device 环球展览公司 2021-08-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250255173-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG MAPT 1640/4885LMNA 1299/4885CYP3A4 480/4885
US-20240206317-A1 ORGANIC METAL COMPLEX AND ORGANIC LIGHT EMITTING ELEMENT ORC3, CRY1, PER2 MAPT 1453/4885LMNA 2761/4885CYP3A4 1530/4885
US-20220352476-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG MAPT 1640/4885LMNA 1299/4885CYP3A4 480/4885
US-12324348-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG MAPT 1640/4885LMNA 1299/4885CYP3A4 480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.