Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256030 | 0.85 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1 | |
| SCHEMBL1087387 | 0.78 | MAPT (0.40) | HSP90AA1HSP90AB1 | |
| SCHEMBL27163379 | 0.77 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1PTPN1 | |
| SCHEMBL410531 | 0.76 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL18255995 | 0.75 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1PTPN1 | |
| SCHEMBL2537212 | 0.75 | MAPT (0.49) | PTPN1 | |
| SCHEMBL8876294 | 0.75 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1 | |
| SCHEMBL1222427 | 0.74 | NOTUM (0.54) | HSP90AA1HSP90AB1PTPN1 | |
| SCHEMBL9902222 | 0.74 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1PTPN1 | |
| SCHEMBL2534822 | 0.73 | SLC6A3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199546-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | HERCULES CAPITAL, INC., AS AGENT | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199546-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | SLC6A19, SLC2A9, SLC6A3 | HSP90AA1 1073/4885HSP90AB1 717/4885PTPN1 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.