Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874054 | 0.81 | ALDH1A1 (0.41) | HSP90AA1HSP90AB1ALDH1A1LMNA | |
| SCHEMBL8874622 | 0.76 | ALDH1A1 (0.38) | HSP90AA1HSP90AB1ALDH1A1LMNA | |
| SCHEMBL18256030 | 0.76 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL27247396 | 0.75 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1 | |
| SCHEMBL8874887 | 0.70 | ALDH1A1 (0.41) | ALDH1A1LMNACYP1A2 | |
| SCHEMBL18255995 | 0.70 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1 | |
| SCHEMBL1087387 | 0.70 | MAPT (0.40) | HSP90AA1HSP90AB1ALDH1A1CYP2D6 | |
| SCHEMBL27163379 | 0.68 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL8876288 | 0.68 | PPARA (0.39) | HSP90AA1HSP90AB1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL410531 | 0.65 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |