Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRPS1 | P60891 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21563347 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL24463279 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL30914190 | 0.81 | PRPS1 (0.43) | PRPS1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL19848258 | 0.76 | DDB1 (0.41) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL12352344 | 0.73 | LMNA (0.42) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL27249523 | 0.72 | DPP4 (0.42) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL27249522 | 0.72 | DPP4 (0.36) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL24463147 | 0.72 | LMNA (0.35) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL21102004 | 0.70 | PRPS1 (0.43) | PRPS1KDM4EADORA2A | |
| SCHEMBL25667797 | 0.69 | ALDH1A1 (0.42) | ALDH1A1KDM4EGLAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077391-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2024-04-18 | — | — | WO | disclosed |