SCHEMBL272500

SCHEMBL272500

BC1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(OC(=O)COc2ccccc2)C1OC

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 5/20 0.43
P2RX2 Q9UBL9 5/20 0.43
P2RX4 Q99571 4/20 0.43
P2RY2 P41231 10/20 0.41
P2RY4 P51582 4/20 0.41
P2RY6 Q15077 2/20 0.41
P2RX1 P51575 2/20 0.38
P2RX7 Q99572 2/20 0.38
ENPP1 P22413 1/20 0.38
P2RY11 Q96G91 2/20 0.37
P2RX6 O15547 1/20 0.37
P2RX5 Q93086 1/20 0.37
NT5E P21589 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272356 0.79 P2RY2 (0.42) P2RX3P2RX2P2RX4P2RY2P2RY4
SCHEMBL271882 0.79 P2RY2 (0.36) P2RX3P2RX2P2RX4P2RY2P2RY4
SCHEMBL18603979 0.79 P2RY2 (0.36) P2RX3P2RX2P2RX4P2RY2P2RY4
SCHEMBL271982 0.74 P2RY2 (0.39) P2RX3P2RX2P2RX4P2RY2P2RY4
SCHEMBL272343 0.73 P2RY2 (0.36) P2RX3P2RX2P2RX4P2RY2P2RY4
SCHEMBL9945522 0.73 P2RY2 (0.45) P2RY2P2RY4P2RY6
SCHEMBL272126 0.72 P2RY2 (0.39) P2RY2P2RY4P2RY6
SCHEMBL271983 0.72 P2RY2 (0.36) P2RX3P2RX2P2RX4P2RY2P2RY4
SCHEMBL272498 0.72 P2RY2 (0.36) P2RX3P2RX2P2RX4P2RY2P2RY4
SCHEMBL13545240 0.71 P2RY2 (0.37) P2RY2P2RY4P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed