SCHEMBL271882

SCHEMBL271882

BC1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(OC(=O)OC)C1OC

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 15/20 0.36
P2RX3 P56373 1/20 0.36
P2RX4 Q99571 1/20 0.36
P2RX2 Q9UBL9 1/20 0.36
P2RY4 P51582 4/20 0.36
P2RY6 Q15077 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18603979 1.00 P2RY2 (0.36) P2RY2P2RX3P2RX4P2RX2P2RY4
SCHEMBL9945522 0.82 P2RY2 (0.45) P2RY2P2RY4P2RY6
SCHEMBL13545240 0.80 P2RY2 (0.37) P2RY2P2RY4P2RY6
SCHEMBL272500 0.79 P2RX3 (0.43) P2RY2P2RX3P2RX4P2RX2P2RY4
SCHEMBL272516 0.77 P2RY2 (0.36) P2RY2P2RY4P2RY6
SCHEMBL272444 0.76 P2RY2 (0.34) P2RY2P2RY4
SCHEMBL23829163 0.74 CA2 (0.43) P2RY2P2RX3P2RX4P2RX2P2RY4
SCHEMBL272126 0.73 P2RY2 (0.39) P2RY2P2RY4P2RY6
SCHEMBL15935859 0.72 FBP1 (0.33) P2RY2P2RY4
SCHEMBL12374598 0.72 FBP1 (0.53) P2RY2P2RX3P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed