Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 8/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.33 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.32 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 2/20 | 0.31 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272356 | 0.92 | P2RY2 (0.42) | P2RY2P2RY4P2RY6P2RX3P2RX2 | |
| SCHEMBL272343 | 0.89 | P2RY2 (0.36) | P2RY2P2RY4P2RY6ALDH1A1P2RX3 | |
| SCHEMBL272498 | 0.85 | P2RY2 (0.36) | P2RY2P2RY4P2RY6ALDH1A1P2RX3 | |
| SCHEMBL272010 | 0.78 | P2RY2 (0.31) | P2RY2 | |
| SCHEMBL271982 | 0.75 | P2RY2 (0.39) | P2RY2P2RY4P2RY6ALDH1A1P2RX3 | |
| SCHEMBL271873 | 0.74 | P2RY2 (0.35) | P2RY2P2RY4P2RY6 | |
| SCHEMBL18924372 | 0.73 | — | — | |
| SCHEMBL272435 | 0.72 | P2RY2 (0.33) | P2RY2 | |
| SCHEMBL272500 | 0.72 | P2RX3 (0.43) | P2RY2P2RY4P2RY6P2RX3P2RX2 | |
| SCHEMBL272676 | 0.72 | ALDH1A1 (0.36) | P2RY2P2RY4P2RY6ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133669-B2 | Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid | TRILINK BIOTECHNOLOGIES (US) | 2012-03-13 | — | — | US | disclosed |
| US-20100003724-A1 | CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID | TriLink Bio Technologies | 2010-01-07 | — | — | US | disclosed |