Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27251962 | 0.90 | ALDH1A1 (0.37) | ALDH1A1KMT2ATSHRHSD17B10MAPK1 | |
| SCHEMBL27251882 | 0.89 | CYP1A2 (0.41) | ALDH1A1KMT2ATSHRHSD17B10MAPK1 | |
| SCHEMBL27251886 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KMT2AAKR1C2AKR1C1TSHR | |
| SCHEMBL27251885 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KMT2AAKR1C2AKR1C1TSHR | |
| SCHEMBL27251881 | 0.85 | CYP1A2 (0.38) | ALDH1A1KMT2ATSHRHSD17B10MAPK1 | |
| SCHEMBL13547631 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KMT2AAKR1C2AKR1C1TSHR | |
| SCHEMBL27251963 | 0.78 | ESR1 (0.44) | ALDH1A1KMT2ATSHRHSD17B10MAPK1 | |
| SCHEMBL11244353 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KMT2ATSHRHSD17B10MAPK1 | |
| SCHEMBL941642 | 0.77 | — | — | |
| SCHEMBL27251980 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KMT2ATSHRHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024480-B2 | Polynitroso compound, its preparation and electrochemical use | CITY UNIVERSITY OF HONG KONG (HK) | 2024-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024480-B2 | Polynitroso compound, its preparation and electrochemical use | PNPO, NOXO1, MT-ND6 | ALDH1A1 1278/4885KMT2A 3019/4885AKR1C2 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.