SCHEMBL27254656

SCHEMBL27254656

CC(=O)Nc1ccc(Cc2ccc(NC(C)=O)c(C)c2)cc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR174 Q9BXC1 1/20 0.57
HPGD P15428 2/20 0.53
ALDH1A1 P00352 2/20 0.53
ESR1 P03372 2/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
LMNA P02545 1/20 0.48
CYP2C9 P11712 1/20 0.48
ESR2 Q92731 1/20 0.47
GAA P10253 2/20 0.46
NPC1 O15118 2/20 0.46
MAPT P10636 2/20 0.46
POLB P06746 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
HTT P42858 2/20 0.45
TSHR P16473 1/20 0.45
NR1H4 Q96RI1 1/20 0.44
KDM4E B2RXH2 1/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13267662 0.91 GPR174 (0.50) GPR174HPGDALDH1A1ESR1MEN1
SCHEMBL7903540 0.87 ESR1 (0.52) GPR174HPGDALDH1A1ESR1MEN1
SCHEMBL11118946 0.87 GPR174 (0.59) GPR174ALDH1A1ESR1MEN1KMT2A
SCHEMBL24201996 0.86 ALDH1A1 (0.50) GPR174HPGDALDH1A1ESR1MEN1
SCHEMBL9339667 0.86 ALDH1A1 (0.50) GPR174HPGDALDH1A1ESR1MEN1
SCHEMBL1285410 0.84 NR1H4 (0.62) GPR174HPGDALDH1A1ESR1MEN1
SCHEMBL11421194 0.84 MEN1 (0.57) GPR174HPGDALDH1A1ESR1MEN1
SCHEMBL3428272 0.83 TSHR (0.48) GPR174HPGDALDH1A1ESR1MEN1
SCHEMBL6106197 0.83 ALDH1A1 (0.47) GPR174HPGDALDH1A1ESR1MEN1
SCHEMBL4393968 0.82 ESR1 (0.51) HPGDALDH1A1ESR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12034115-B2 Solid electrolyte composition, sheet for all-solid state secondary battery, electrode sheet for all-solid state secondary battery, and all-solid state secondary battery FUJIFILM CORPORATION (JP) 2024-07-09 US disclosed
US-20240213479-A1 ELECTRODE COMPOSITION, ELECTRODE SHEET FOR ALL-SOLID STATE SECONDARY BATTERY, ALL-SOLID STATE SECONDARY BATTERY, AND MANUFACTURING METHODS FOR ELECTRODE COMPOSITION, ELECTRODE SHEET FOR ALL-SOLID STATE SECONDARY BATTERY, AND ALL-SOLID STATE SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2024-06-27 US disclosed