SCHEMBL11118946

SCHEMBL11118946

Cc1cc(Cc2ccc(NC(=O)O)c(C)c2)ccc1NC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR174 Q9BXC1 1/20 0.59
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
NR1H4 Q96RI1 1/20 0.49
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
KDM4E B2RXH2 1/20 0.47
PKM P14618 1/20 0.47
GAA P10253 2/20 0.47
TDP1 Q9NUW8 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HTT P42858 1/20 0.46
LTC4S Q16873 1/20 0.45
TP53 P04637 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP3A4 P08684 1/20 0.44
RECQL P46063 1/20 0.44
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27254656 0.87 GPR174 (0.57) GPR174MEN1KMT2ANR1H4ESR1
SCHEMBL11068324 0.85 MEN1 (0.47) GPR174MEN1KMT2ANR1H4SMN1; SMN2
SCHEMBL13129153 0.83 LTC4S (0.68) GPR174MEN1KMT2ANR1H4ALDH1A1
SCHEMBL11037935 0.83 GAA (0.50) GPR174MEN1KMT2AESR1ESR2
SCHEMBL11421194 0.82 MEN1 (0.57) GPR174MEN1KMT2AESR1ESR2
SCHEMBL23093237 0.81 CYP4A11 (0.45) GPR174MEN1KMT2ANR1H4GAA
SCHEMBL11672440 0.81 GPR174 (0.52) GPR174MEN1KMT2ANR1H4ESR1
SCHEMBL2091990 0.81 GPR174 (0.52) GPR174MEN1KMT2ATDP1SMN1; SMN2
SCHEMBL9467160 0.80 RAB9A (0.60) GPR174MEN1KMT2ATDP1ALDH1A1
SCHEMBL23092991 0.80 NR1H4 (0.43) GPR174MEN1KMT2ANR1H4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4476317-A HETEROPOLYMOLYBDIC ACID OR HETEROPOLYTUNGSTIC ACID MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1984-10-09 US disclosed