SCHEMBL27256210

SCHEMBL27256210

CC(=O)C[C@H]1CC[C@H](Oc2ccc3oc4ccccc4c(=O)c3c2)CC1

nearest known ligand 0.82

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ACSL1 P33121 4/20 0.82
▸ ACSL6 Q9UKU0 3/20 0.69
▸ ACSL3 O95573 1/20 0.69
▸ MAOA P21397 3/20 0.52
▸ NPC1 O15118 4/20 0.48
▸ RAB9A P51151 4/20 0.48
▸ POLB P06746 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ MAOB P27338 6/20 0.46
▸ HRH3 Q9Y5N1 6/20 0.46
▸ CASP3 P42574 1/20 0.44
▸ SENP8 Q96LD8 1/20 0.44
▸ SENP7 Q9BQF6 1/20 0.44
▸ SENP6 Q9GZR1 1/20 0.44
▸ TTR P02766 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24634626 0.90 ACSL1 (1.00) ACSL1ACSL6ACSL3MAOANPC1
SCHEMBL27256207 0.85 ACSL1 (0.81) ACSL1ACSL6ACSL3MAOANPC1
SCHEMBL27256174 0.85 ACSL1 (0.81) ACSL1ACSL6ACSL3MAOANPC1
SCHEMBL26780273 0.82 ACSL1 (1.00) ACSL1ACSL6ACSL3MAOANPC1
SCHEMBL24634565 0.82 ACSL1 (1.00) ACSL1ACSL6ACSL3MAOANPC1
SCHEMBL25524814 0.73 MAOA (0.68) ACSL1ACSL6ACSL3MAOANPC1
SCHEMBL392389 0.72 MAOA (0.70) ACSL1ACSL6MAOANPC1RAB9A
SCHEMBL30130333 0.72 MAOA (0.70) ACSL1ACSL6MAOANPC1RAB9A
SCHEMBL27256204 0.71 ACSL1 (0.80) ACSL1ACSL6MAOANPC1RAB9A
SCHEMBL27256205 0.70 ACSL1 (0.80) ACSL1ACSL6MAOAMAOBHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207270-A1 COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM WAVEBREAK INC (US) 2024-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207270-A1 COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM CPT2, PC, SREBF2 ACSL1 90/4885ACSL6 72/4885ACSL3 129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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