SCHEMBL27256909

SCHEMBL27256909

CCCCC(CC)CNc1nc(Nc2ccc3[nH]c(=O)[nH]c3c2)nc(C(C)(C)S)n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.34
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ MAPT P10636 6/20 0.33
▸ MEN1 O00255 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ TSHR P16473 2/20 0.33
▸ CASP1 P29466 2/20 0.33
▸ HBB P68871 1/20 0.33
▸ AURKA O14965 1/20 0.33
▸ AURKB Q96GD4 1/20 0.33
▸ NPY5R Q15761 1/20 0.33
▸ ALDH1A1 P00352 5/20 0.33
▸ HTT P42858 1/20 0.33
▸ JAK1 P23458 1/20 0.33
▸ JAK3 P52333 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.32
▸ USP2 O75604 1/20 0.32
▸ TP53 P04637 1/20 0.32
▸ XBP1 P17861 1/20 0.32
▸ RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23666322 0.93 POLB (0.35) POLBSMN1; SMN2MAPTMEN1KMT2A
SCHEMBL23786208 0.86 SMN1; SMN2 (0.36) POLBSMN1; SMN2MAPTMEN1KMT2A
SCHEMBL23139609 0.73 AURKA (0.46) POLBSMN1; SMN2MAPTMEN1KMT2A
SCHEMBL23139618 0.70 CA1 (0.43) POLBMAPTMEN1KMT2ATSHR
SCHEMBL7776211 0.67 ALDH1A1 (0.57) POLBSMN1; SMN2KMT2ATSHRNPY5R
SCHEMBL23139614 0.67 GAA (0.47) POLBSMN1; SMN2MAPTMEN1KMT2A
SCHEMBL23786325 0.67 CA1 (0.48) POLBSMN1; SMN2MAPTMEN1KMT2A
SCHEMBL23666320 0.67 RAB9A (0.44) POLBMAPTMEN1KMT2ATSHR
SCHEMBL23786206 0.66 MAPT (0.48) POLBSMN1; SMN2MAPTMEN1KMT2A
SCHEMBL23139623 0.66 KDM4E (0.42) POLBSMN1; SMN2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12019371-B2 Photosensitive composition, film, color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2024-06-25 — — US disclosed
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