Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967052 | 1.00 | ALDH1A1 (0.34) | ALDH1A1GAASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL27257576 | 0.84 | LMNA (0.34) | — | |
| SCHEMBL30967123 | 0.78 | GAA (0.31) | GAA | |
| SCHEMBL27257009 | 0.78 | GAA (0.31) | GAA | |
| SCHEMBL27256666 | 0.75 | GRIN1 (0.32) | — | |
| SCHEMBL1554935 | 0.74 | SMN1; SMN2 (0.40) | ALDH1A1GAASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL30967140 | 0.73 | KCNQ3 (0.33) | — | |
| SCHEMBL27257213 | 0.73 | — | — | |
| SCHEMBL27257412 | 0.73 | KCNQ3 (0.33) | — | |
| SCHEMBL19174276 | 0.73 | ALDH1A1 (0.38) | ALDH1A1GAASMN1; SMN2L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618974-A1 | OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107615-A1 | OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024107615-A1 | OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-23 | — | — | WO | disclosed |