Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2638021 | 0.91 | MMP8 (0.43) | MMP8ALDH1A1TSHRGAAMGAM | |
| SCHEMBL4968775 | 0.84 | LMNA (0.30) | LMNA | |
| SCHEMBL2732715 | 0.83 | TDP1 (0.37) | MMP8ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL4377134 | 0.80 | MMP8 (0.36) | MMP8ALDH1A1TSHRGAAMGAM | |
| SCHEMBL4382740 | 0.79 | MEN1 (0.37) | MMP8ALDH1A1TSHRGAAMGAM | |
| SCHEMBL2410161 | 0.79 | MMP8 (0.49) | MMP8ALDH1A1TSHRGAAMGAM | |
| SCHEMBL14016347 | 0.77 | MEN1 (0.46) | ALDH1A1TSHRGAAMGAMSI | |
| SCHEMBL4380430 | 0.77 | MEN1 (0.36) | MMP8ALDH1A1TSHRGAAMGAM | |
| SCHEMBL28464690 | 0.77 | MEN1 (0.41) | MMP8ALDH1A1TSHRGAAMGAM | |
| SCHEMBL28963018 | 0.76 | MMP8 (0.46) | MMP8ALDH1A1TSHRGAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059797-A1 | PROCESS FOR SYNTHESIS OF (S) - PREGABALIN | LUPIN LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |
| WO-2012059797-A1 | PROCESS FOR SYNTHESIS OF (S) - PREGABALIN | LUPIN LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |