Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 6/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27259343 | 0.84 | PTPN7 (0.46) | SMN1; SMN2EGLN1PPARGFFAR1 | |
| SCHEMBL27259397 | 0.81 | FFAR1 (0.47) | SMN1; SMN2FFAR1 | |
| SCHEMBL27259261 | 0.81 | PTPN7 (0.46) | PPARDSMN1; SMN2EGLN1 | |
| SCHEMBL27259321 | 0.81 | CTRC (0.47) | SMN1; SMN2EGLN1PTGDR2 | |
| SCHEMBL10944778 | 0.81 | LMNA (0.62) | SMN1; SMN2EGLN1 | |
| SCHEMBL27259375 | 0.79 | PTPN7 (0.43) | SMN1; SMN2EGLN1FFAR1 | |
| SCHEMBL27259361 | 0.79 | PPARD (0.44) | PPARDPPARASMN1; SMN2PTGDR2SCN9A | |
| SCHEMBL10946840 | 0.78 | PPARD (0.63) | PPARDPPARAPTPN1SMN1; SMN2PPARG | |
| SCHEMBL27259460 | 0.77 | MEN1 (0.52) | SMN1; SMN2PTGDR2 | |
| SCHEMBL27259368 | 0.77 | PDE4B (0.52) | PTPN1SMN1; SMN2EGLN1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132001-A1 | MULTITARGET NUCLEAR RECEPTOR LIGANDS BASED ON 2-(4-(QUINOLIN-2-YLOXY)PHENOXY)PROPANOIC ACID AND 2-(4-(QUINOXALIN-2-YLOXY)PHENOXY)PROPANOIC ACID FOR THE TREATMENT OF METABOLIC AND LIVER DISEASES | CHARLES UNIVERSITY, FACULTY OF PHARMACY IN HRADEC KRALOVE (CZ) | 2024-06-27 | — | — | WO | disclosed |