Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13349554 | 0.87 | L3MBTL1 (0.58) | FFAR1MCL1L3MBTL1 | |
| SCHEMBL27259726 | 0.85 | HTT (0.53) | FFAR1KDM4EPTPN7NR4A1APEX1 | |
| SCHEMBL27259375 | 0.85 | PTPN7 (0.43) | FFAR1PTPN7SMN1; SMN2ALOX15ACACA | |
| SCHEMBL27259343 | 0.84 | PTPN7 (0.46) | FFAR1PTPN7SMN1; SMN2ALOX15MEN1 | |
| SCHEMBL27259321 | 0.84 | CTRC (0.47) | PTPN7SMN1; SMN2ALOX15TDP1MEN1 | |
| SCHEMBL27259261 | 0.84 | PTPN7 (0.46) | PTPN7APEX1MCL1SMN1; SMN2ALOX15 | |
| SCHEMBL13316456 | 0.81 | KMT2A (0.57) | KDM4ETDP1MEN1KMT2ANPC1 | |
| SCHEMBL27259359 | 0.81 | PPARD (0.49) | FFAR1SMN1; SMN2 | |
| SCHEMBL27259460 | 0.80 | MEN1 (0.52) | PTPN7SMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL10299391 | 0.78 | PTPN7 (0.71) | FFAR1KDM4EPTPN7NR4A1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132001-A1 | MULTITARGET NUCLEAR RECEPTOR LIGANDS BASED ON 2-(4-(QUINOLIN-2-YLOXY)PHENOXY)PROPANOIC ACID AND 2-(4-(QUINOXALIN-2-YLOXY)PHENOXY)PROPANOIC ACID FOR THE TREATMENT OF METABOLIC AND LIVER DISEASES | CHARLES UNIVERSITY, FACULTY OF PHARMACY IN HRADEC KRALOVE (CZ) | 2024-06-27 | — | — | WO | disclosed |