Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CFD | P00746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27424167 | 0.90 | TSHR (0.55) | KDM4EALDH1A1TSHRGAARAB9A | |
| SCHEMBL27406467 | 0.81 | TSHR (0.41) | KDM4EALDH1A1TSHRGAARAB9A | |
| SCHEMBL8785740 | 0.78 | PTGS2 (0.50) | TSHRRAB9APKMLMNATTR | |
| SCHEMBL8090536 | 0.76 | PTGS2 (0.47) | KDM4ETSHRRAB9APKMHPGD | |
| SCHEMBL29612133 | 0.75 | PTGS2 (0.55) | TSHRRAB9APKMLMNATTR | |
| SCHEMBL7652014 | 0.75 | PTGS2 (0.55) | TSHRRAB9APKMLMNATTR | |
| SCHEMBL27371818 | 0.72 | TSHR (0.53) | TSHRGAAMEN1LMNAMAPT | |
| SCHEMBL28391763 | 0.72 | L3MBTL1 (0.41) | KDM4EALDH1A1TSHRGAARAB9A | |
| 3,4,5-Triacetoxybenzoic Acid SCHEMBL716891 | 0.72 | KDM4E (0.63) | KDM4EALDH1A1TSHRGAARAB9A | |
| SCHEMBL8830887 | 0.72 | KDM4E (0.63) | KDM4EALDH1A1TSHRGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1025737-C | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-08-24 | — | — | CN | disclosed |
| CN-1038814-A | Cephem compound and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1990-01-17 | — | — | CN | disclosed |