Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28507548 | 0.79 | KDM4E (0.58) | KDM4EKMT2AMAPTMAPK1CYP19A1 | |
| SCHEMBL29816056 | 0.78 | KDM4E (0.47) | KDM4EKMT2AMAPTMAPK1CYP19A1 | |
| SCHEMBL194441 | 0.78 | ATM (0.50) | KDM4EKMT2AMAPTMAPK1CYP19A1 | |
| SCHEMBL7820572 | 0.78 | MAOA (0.47) | KDM4EKMT2AMAPTMAPK1CYP19A1 | |
| SCHEMBL8781658 | 0.76 | AHR (0.41) | KDM4EKMT2AMAPTGAAHPGD | |
| SCHEMBL194725 | 0.75 | ALDH1A1 (0.54) | KDM4EKMT2AMAPTMAPK1CYP19A1 | |
| SCHEMBL29815772 | 0.75 | KDM4E (0.41) | KDM4EKMT2AMAPTMAPK1CYP19A1 | |
| SCHEMBL193958 | 0.75 | KDM4E (0.41) | KDM4EKMT2AMAPTMAPK1CYP19A1 | |
| SCHEMBL9263369 | 0.74 | ALDH1A1 (0.52) | KDM4EKMT2AMAPTMAPK1CYP19A1 | |
| SCHEMBL194493 | 0.73 | MAOA (0.41) | KDM4EKMT2AMAPTMAPK1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1026206-C | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for preparation thereof | AMERICAN CYANAMID CO (US) | 1994-10-19 | — | — | CN | disclosed |
| CN-1039807-A | Desinsection, kill mite, nematocides aryl-pyrrolidine and preparation method thereof | AMERICAN CYANAMID CO (US) | 1990-02-21 | — | — | CN | disclosed |