SCHEMBL194493

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29816227	0.81	MAP2K2 (0.60)	MAOAMAOBCYP19A1KDM4EL3MBTL1
	SCHEMBL194257	0.81	MAP2K2 (0.60)	MAOAMAOBCYP19A1KDM4EL3MBTL1
	SCHEMBL194258	0.78	CDC7 (0.46)	KDM4EL3MBTL1MAPTKMT2AMAPK1
	SCHEMBL193958	0.78	KDM4E (0.41)	MAOAMAOBCYP19A1KDM4EL3MBTL1
	SCHEMBL29815772	0.78	KDM4E (0.41)	MAOAMAOBCYP19A1KDM4EL3MBTL1
	SCHEMBL194587	0.78	KDM4E (0.49)	MAOAMAOBCYP19A1KDM4EL3MBTL1
	SCHEMBL194441	0.76	ATM (0.50)	MAOAMAOBCYP19A1KDM4EMAPT
	SCHEMBL194725	0.73	ALDH1A1 (0.54)	MAOAMAOBCYP19A1KDM4EMAPT
	SCHEMBL193704	0.73	CYP19A1 (0.47)	MAOAMAOBCYP19A1MAPTKMT2A
	SCHEMBL27260366	0.73	KDM4E (0.47)	MAOAMAOBCYP19A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.