Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24217799 | 0.98 | LIPG (0.50) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL11126243 | 0.92 | LIPG (0.43) | LIPGNR1H2NR1H3TSHRALOX5 | |
| Water SCHEMBL28085363 | 0.86 | LIPG (0.67) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL7781555 | 0.84 | ALDH1A1 (0.44) | LIPGPPARGPPARA | |
| SCHEMBL10980560 | 0.84 | LIPG (0.69) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL1343771 | 0.84 | LIPG (0.69) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL7516668 | 0.84 | LIPG (0.69) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL18496530 | 0.84 | LIPG (0.69) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL7534048 | 0.84 | LIPG (0.69) | LIPGNR1H2NR1H3BIDMCL1 | |
| SCHEMBL10755599 | 0.84 | LIPG (0.69) | LIPGNR1H2NR1H3BIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1025564-C | Process for the preparation of phenyl epoxy hydroxy acid esters | SMITHKLINE BECKMAN CORP (US) | 1994-08-03 | — | — | CN | disclosed |
| CN-1008091-B | Process for preparing leukotriene antagonists | SMITHKLINE BECKMAN CORP (US) | 1990-05-23 | — | — | CN | disclosed |
| CN-1040586-A | Process for preparing leukotriene antagonists | SMITHKLINE BECKMAN CORP (US) | 1990-03-21 | — | — | CN | disclosed |
| CN-86102482-A | Process for preparing leukotriene antagonists | — | 1987-02-04 | — | — | CN | disclosed |