Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1606849 | 0.77 | CNR2 (0.42) | LMNA | |
| SCHEMBL10900970 | 0.76 | LMNA (0.55) | EPHX2PPARGLMNAMAP3K14PPARA | |
| SCHEMBL21525571 | 0.76 | LMNA (0.51) | EPHX2PPARGLMNAMAP3K14PPARA | |
| SCHEMBL31466359 | 0.76 | LMNA (0.77) | EPHX2PPARGLMNAMAP3K14PPARA | |
| Bicarbonate SCHEMBL27586024 | 0.76 | LIPG (0.52) | PPARGPPARABIDMCL1BCL2L1 | |
| SCHEMBL10690999 | 0.75 | LMNA (0.48) | EPHX2PPARGLMNAMAP3K14PPARA | |
| SCHEMBL26246525 | 0.75 | EPHX2 (0.50) | EPHX2PPARGLMNAMAP3K14PPARA | |
| SCHEMBL2451895 | 0.74 | CDC25A (0.46) | — | |
| SCHEMBL9022355 | 0.74 | RARB (0.57) | EPHX2AGTR1AGTR2 | |
| Phthalic Acid SCHEMBL8813342 | 0.73 | ALDH1A1 (0.54) | PPARGPPARABIDMCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1022754-C | Novel aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds preparation method | MERRELL DOW PHARMA (US) | 1993-11-17 | — | — | CN | disclosed |
| CN-1044653-A | The new aryl or the heteroaryl-I-alkyl-pyrroles-2-carboxylic acid that are used for the treatment of the pathological state of interleukin-I mediation | MERRELL DOW PHARMA (US) | 1990-08-15 | — | — | CN | disclosed |