SCHEMBL27263227

SCHEMBL27263227

COC(=O)c1cccnc1S(=O)(=O)NC(=O)Nc1cc(OC)cc(OC)n1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
FBP1 P09467 2/20 0.39
CREBBP Q92793 1/20 0.39
SLC40A1 Q9NP59 1/20 0.38
KDM4E B2RXH2 4/20 0.38
HSD17B10 Q99714 3/20 0.38
GLA P06280 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
RXFP1 Q9HBX9 1/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7803569 0.89 CDK1 (0.44) GAAFBP1CREBBPTDP1MEN1
SCHEMBL27351851 0.87 GAA (0.40) GAAFBP1CREBBPSLC40A1HSD17B10
SCHEMBL10875769 0.86 GAA (0.40) GAAFBP1CREBBPSLC40A1KDM4E
SCHEMBL10875764 0.86 GAA (0.40) GAAFBP1CREBBPSLC40A1KDM4E
SCHEMBL9363807 0.86 FBP1 (0.37) GAAFBP1CREBBPMEN1KMT2A
SCHEMBL9628294 0.85 GAA (0.56) GAASLC40A1GLAMEN1KMT2A
SCHEMBL27614193 0.84 MEN1 (0.48) GAAFBP1CREBBPSLC40A1KDM4E
SCHEMBL2954512 0.84 FBP1 (0.40) GAAFBP1CREBBPSLC40A1GLA
SCHEMBL27303738 0.84 GAA (0.41) GAAFBP1CREBBPSLC40A1KDM4E
SCHEMBL7760051 0.84 GAA (0.41) GAAFBP1CREBBPSLC40A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1023680-C Herbicidal pyridine sulfonylureas DU PONT (US) 1994-02-09 CN disclosed
CN-1040728-A WATER-SOLUBLE OR WATER-DISPERSIBLE PESTICIDE GRANULES DU PONT (US) 1990-03-28 CN disclosed
CN-1035287-A The neighbour of weeding-methoxycarbonyl sulfonylurea DU PONT (US) 1989-09-06 CN disclosed
CN-87107320-A Herbicidal pyridine sulfonylureas 1988-12-07 CN disclosed