SCHEMBL7803569

SCHEMBL7803569

COc1cc(NC(=O)NS(=O)(=O)c2ncccc2C(=O)N(C)C)nc(OC)c1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.44
GAA P10253 1/20 0.38
FBP1 P09467 2/20 0.37
CREBBP Q92793 1/20 0.37
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
RXFP1 Q9HBX9 1/20 0.35
EGLN1 Q9GZT9 1/20 0.34
THRB P10828 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9363807 0.91 FBP1 (0.37) CDK1GAAFBP1CREBBPMEN1
SCHEMBL27263227 0.89 GAA (0.40) GAAFBP1CREBBPMEN1KMT2A
SCHEMBL27259233 0.86 CDK1 (0.48) CDK1GAAFBP1CREBBPMEN1
SCHEMBL27966147 0.86 CDK1 (0.48) CDK1GAAFBP1CREBBPMEN1
Nicosulfuron SCHEMBL8536419 0.86 CDK1 (0.59) CDK1GAAMEN1KMT2AMAPT
Nicosulfuron SCHEMBL22938 0.86 CDK1 (0.59) CDK1GAAMEN1KMT2AMAPT
Nicosulfuron SCHEMBL29440408 0.86 CDK1 (0.59) CDK1GAAMEN1KMT2AMAPT
SCHEMBL27259474 0.85 CDK1 (0.49) CDK1GAAFBP1CREBBPMEN1
Nicosulfuron SCHEMBL15524973 0.85 CDK1 (0.58) CDK1GAAMEN1KMT2AMAPT
Nicosulfuron SCHEMBL28975699 0.85 CDK1 (0.58) CDK1GAAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103987256-A Herbicidal suspension concentrate JIANGSU ROTAM CHEMISTRY CO LTD 2014-08-13 CN claimed
CN-1094039-C Chemically stabilized herbicidal oil-based suspensions ISHIHARA SANGYO KAISHA (JP) 2002-11-13 CN claimed
CN-1311999-A Chamically stabilized herbicidal oil-base suspended matter ISHIHARA SANGYO KAISHA (JP) 2001-09-12 CN claimed
CN-1061214-C Method for enhancing activity of herbicidal composition and herbicidal composition with enhanced activity ISHIHARA SANGYO KAISHA (JP) 2001-01-31 CN claimed
CN-1089431-A Method for enhancing herbicidal activity, herbicidal composition with enhanced activity and composition with enhanced activity ISHIHARA SANGYO KAISHA (JP) 1994-07-20 CN claimed
CN-103987256-A Herbicidal suspension concentrate JIANGSU ROTAM CHEMISTRY CO LTD 2014-08-13 CN disclosed
US-20010056040-A1 Controlling weeds; synergistic mixtures BAYER AKTIENGESELLSCHAFT KONZERNBEREICH RP PATENT UND LIZENZEN (DE) 2001-12-27 US disclosed
CN-1042690-C Herbicidal composition containing substituted pyridinesulfonamide compounds ISHIHARA SANGYO KAISHA (JP) 1999-03-31 CN disclosed
CN-1032137-C Process for preparing substituted pyridine sulfonamides ISHIHARA SANGYO KAISHA (JP) 1996-06-26 CN disclosed
CN-1025812-C Herbicidal suspension concentrage ISHIHARA SANGYO KAISHA (JP) 1994-09-07 CN disclosed
CN-1062352-A The method of the pyridinsulfonamide compounds that preparation replaces ISHIHARA SANGYO KAISHA (JP) 1992-07-01 CN disclosed
CN-1062263-A The weed killer herbicide that contains the pyridinsulfonamide compounds of replacement ISHIHARA SANGYO KAISHA (JP) 1992-07-01 CN disclosed
CN-1016661-B Herbicidal composition containing pyridine sulfonamide ISHIHARA SANGYO KAISHA (JP) 1992-05-20 CN disclosed
CN-1032729-A HERBICIDAL SUSPENSION CONCENTRAGE ISHIHARA SANGYO KAISHA (JP) 1989-05-10 CN disclosed
CN-87100436-A Substituted pyridine sulfonamide compounds, herbicides containing the same, and process for preparing the same 1987-08-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010056040-A1 Controlling weeds; synergistic mixtures AS3MT, OSR1, MSRB3 CDK1 2606/4885GAA 2638/4885FBP1 945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.