Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 3/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27263869 | 0.85 | PSEN1 (0.38) | CTSLCTSBCTSSACP3CTSK | |
| SCHEMBL30372442 | 0.85 | ACP3 (0.49) | CPN1CPB2ACP3PSEN1PSEN2 | |
| SCHEMBL5329154 | 0.83 | CYP2C19 (0.47) | CPN1CPB2CTSSCTSK | |
| SCHEMBL27264382 | 0.83 | CPN1 (0.42) | CPN1CPB2CTSLCTSBCTSS | |
| SCHEMBL499473 | 0.80 | PSEN1 (0.50) | CPN1CPB2ACP3PSEN1PSEN2 | |
| SCHEMBL14359741 | 0.80 | TBXAS1 (0.44) | CPN1CPB2ACP3PSEN1PSEN2 | |
| SCHEMBL27266168 | 0.80 | CPB2 (0.46) | CPN1CPB2ACP3PSEN1PSEN2 | |
| SCHEMBL29116712 | 0.79 | CPN1 (0.46) | CPN1CPB2ACP3SLC6A9PTGFR | |
| SCHEMBL27491134 | 0.79 | SLC6A9 (0.45) | CPN1CPB2ACP3SLC6A9PTGFR | |
| SCHEMBL31626010 | 0.79 | CPN1 (0.41) | CPN1CPB2CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054845-A1 | MACROCYCIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |