Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955298 | 0.83 | SLC6A2 (0.37) | NUDT1BACE1DRD2 | |
| SCHEMBL23278109 | 0.80 | GSR (0.45) | HRH3 | |
| SCHEMBL27261887 | 0.77 | NUDT1 (0.39) | NUDT1BACE1CSNK2A1DRD2HRH3 | |
| SCHEMBL19658033 | 0.75 | CSNK2A1 (0.43) | CSNK2A1HRH3 | |
| SCHEMBL16960235 | 0.74 | TRPA1 (0.48) | — | |
| SCHEMBL62964 | 0.73 | NUDT1 (0.42) | NUDT1BACE1CSNK2A1 | |
| SCHEMBL21756929 | 0.73 | GABRA1 (0.36) | — | |
| SCHEMBL26080932 | 0.73 | PTGDR2 (0.42) | — | |
| SCHEMBL16960232 | 0.73 | TRPA1 (0.31) | — | |
| SCHEMBL10094428 | 0.73 | F2RL1 (0.43) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023201282-A1 | NOVEL GSPT1 COMPOUNDS AND METHODS OF USE OF THE NOVEL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-19 | — | — | WO | disclosed |