Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | IL1RN | P18510 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4260025 | 0.82 | HPGD (0.60) | ALDH1A1HPGDKDM4EMEN1GAA | |
| Isophthalic Acid SCHEMBL28737082 | 0.81 | KMO (0.58) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| Isophthalic Acid SCHEMBL27899309 | 0.81 | HPGD (0.61) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL4696934 | 0.79 | L3MBTL3 (0.72) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| Isophthalic Acid SCHEMBL27962393 | 0.79 | KMO (0.60) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| Isophthalic Acid SCHEMBL6857089 | 0.79 | KMO (0.60) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| Isophthalic Acid SCHEMBL259039 | 0.79 | KMO (0.60) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL3319386 | 0.79 | ALDH1A1 (0.73) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| Isophthalic Acid SCHEMBL30529662 | 0.79 | CA12 (0.65) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| Isophthalic Acid SCHEMBL28075948 | 0.79 | CYP2D6 (0.56) | ALDH1A1HPGDHSD17B10KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1021652-C | Process for the preparation of substituted N- (1-alkyl-3-hydroxy-4-piperidinyl) benzamides | JANSSEN PHARMACEUTIEA N V (BE) | 1993-07-21 | — | — | CN | disclosed |
| CN-1067889-A | The preparation method of N-(the 1-alkyl-3-hydroxy-4-piperidinyl base) benzamide that replaces | JANSSEN PHARMACEUTICA NV (BE) | 1993-01-13 | — | — | CN | disclosed |
| CN-1032438-A | Novel substituted N- (1-alkyl-3-hydroxy-4-piperidinyl) benzamides | JANSSEN PHARMACEUTICA NV (BE) | 1989-04-19 | — | — | CN | disclosed |