Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL27288925 | 0.81 | HSD17B10 (0.52) | RECQLALDH1A1SMN1; SMN2MAPK1 | |
| Benzene SCHEMBL27632184 | 0.77 | SIGMAR1 (0.44) | ADRB1HTR7ALDH1A1POLBHTR6 | |
| SCHEMBL113133 | 0.76 | HTR7 (0.60) | MAPTRECQLADRB1SIRT6HTR7 | |
| SCHEMBL29876153 | 0.76 | HTR7 (0.60) | MAPTRECQLADRB1SIRT6HTR7 | |
| Hydrochloric Acid SCHEMBL29947196 | 0.75 | MAPT (0.59) | MAPTRECQLADRB1SIRT6HTR7 | |
| Hydrochloric Acid SCHEMBL15821250 | 0.75 | MAPT (0.59) | MAPTRECQLADRB1SIRT6HTR7 | |
| SCHEMBL7821226 | 0.75 | HTT (0.61) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL27276371 | 0.74 | SIGMAR1 (0.41) | ADRB1ALDH1A1SMN1; SMN2POLBHTR6 | |
| SCHEMBL28118979 | 0.74 | TSHR (0.49) | MAPTADRB1HTR7ALDH1A1POLB | |
| SCHEMBL10578128 | 0.74 | CA2 (0.35) | ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1016171-B | Synthesis method of high-purity P, P' -diaminobenzoyl piperazine | UNIV SHANGHAI (CN) | 1992-04-08 | — | — | CN | claimed |
| CN-1039020-A | High purity P, P '-diaminobenzene formyl piperazine synthetic | UNIV SHANGHAI (CN) | 1990-01-24 | — | — | CN | claimed |
| CN-1016171-B | Synthesis method of high-purity P, P' -diaminobenzoyl piperazine | UNIV SHANGHAI (CN) | 1992-04-08 | — | — | CN | disclosed |
| CN-1039020-A | High purity P, P '-diaminobenzene formyl piperazine synthetic | UNIV SHANGHAI (CN) | 1990-01-24 | — | — | CN | disclosed |
| CN-1039020-A | High purity P, P '-diaminobenzene formyl piperazine synthetic | UNIV SHANGHAI (CN) | 1990-01-24 | — | — | CN | disclosed |