Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27273042 | 0.90 | ALDH1A1 (0.44) | KDM4EMAPTPKMALDH1A1HPGD | |
| SCHEMBL30987632 | 0.90 | ALDH1A1 (0.44) | KDM4EMAPTPKMALDH1A1HPGD | |
| SCHEMBL18561359 | 0.79 | ADORA2A (0.47) | NPC1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL28472884 | 0.78 | TLR8 (0.41) | NPC1KDM4EMAPTPKMALDH1A1 | |
| SCHEMBL31173872 | 0.78 | MAPT (0.50) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL20604896 | 0.78 | MAPT (0.44) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL14737303 | 0.78 | MAPT (0.50) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL30987624 | 0.78 | MAPT (0.44) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL18561358 | 0.77 | CYSLTR2 (0.42) | NPC1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL27273043 | 0.77 | HCAR3 (0.51) | KDM4EALDH1A1HPGDCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133560-A1 | IMIDAZO[1,2-A]PYRIDINE AND IMIDAZO[1,2-A]PYRAZINE DERIVATIVES AS MLLT1 AND MLLT3 INHIBITORS | DARK BLUE THERAPEUTICS LTD (GB) | 2024-06-27 | — | — | WO | disclosed |