Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28468125 | 0.91 | LOXL2 (0.46) | TLR8ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL7658563 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL27272748 | 0.85 | SLC22A12 (0.44) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL7656202 | 0.85 | KDM4E (0.38) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL8682731 | 0.83 | KDM4E (0.39) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL7658111 | 0.81 | KDM4E (0.37) | TLR8ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL23559702 | 0.80 | KDM4E (0.50) | TLR8ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL7655673 | 0.79 | LMNA (0.47) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL7651382 | 0.79 | BACE1 (0.42) | TLR8ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL7651372 | 0.79 | ALDH1A1 (0.37) | TLR8ALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825595-A | Sodium channel blockers | 山东轩竹医药科技有限公司 | 2020-10-27 | — | — | CN | disclosed |