Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929327 | 0.87 | KAT6A (0.56) | KAT6ALMNANOTUMERCC1ERCC4 | |
| SCHEMBL31173853 | 0.85 | LMNA (0.56) | KAT6ALMNANOTUMERCC1ERCC4 | |
| SCHEMBL29488339 | 0.85 | KAT6A (0.59) | KAT6ALMNAERCC1ERCC4FFAR4 | |
| SCHEMBL2161445 | 0.85 | LMNA (0.56) | KAT6ALMNANOTUMERCC1ERCC4 | |
| SCHEMBL940668 | 0.85 | KAT6A (0.59) | KAT6ALMNAERCC1ERCC4FFAR4 | |
| SCHEMBL9807573 | 0.84 | KAT6A (0.54) | KAT6ALMNANOTUMERCC1ERCC4 | |
| SCHEMBL16220632 | 0.84 | KAT6A (0.54) | KAT6ALMNANOTUMERCC1ERCC4 | |
| SCHEMBL1019716 | 0.81 | NOTUM (0.59) | LMNANOTUMALDH1A1KDM4EMAPK1 | |
| SCHEMBL27931328 | 0.81 | ELANE (0.56) | KAT6ALMNAERCC1ERCC4ALDH1A1 | |
| SCHEMBL23889033 | 0.80 | KAT6A (0.51) | KAT6ALMNANOTUMERCC1ERCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133560-A1 | IMIDAZO[1,2-A]PYRIDINE AND IMIDAZO[1,2-A]PYRAZINE DERIVATIVES AS MLLT1 AND MLLT3 INHIBITORS | DARK BLUE THERAPEUTICS LTD (GB) | 2024-06-27 | — | — | WO | disclosed |