Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940668 | 1.00 | KAT6A (0.59) | KAT6ALMNAHTTMEN1KMT2A | |
| SCHEMBL5929327 | 0.88 | KAT6A (0.56) | KAT6ALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2161445 | 0.87 | LMNA (0.56) | KAT6ALMNAKMT2AALDH1A1GAA | |
| SCHEMBL31173853 | 0.87 | LMNA (0.56) | KAT6ALMNAKMT2AALDH1A1GAA | |
| SCHEMBL9807573 | 0.85 | KAT6A (0.54) | KAT6ALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL27273126 | 0.85 | KAT6A (0.54) | KAT6ALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL16220632 | 0.85 | KAT6A (0.54) | KAT6ALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL6607286 | 0.83 | LMNA (0.64) | KAT6ALMNAHTTKMT2AALDH1A1 | |
| SCHEMBL1645251 | 0.83 | LMNA (0.52) | KAT6ALMNAHTTALDH1A1KDM4E | |
| SCHEMBL27931328 | 0.83 | ELANE (0.56) | KAT6ALMNAKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-114206856-A | Anti-malarial hexahydropyrimidine analogues | UCB生物制药有限责任公司 | 2022-03-18 | — | — | CN | disclosed |