SCHEMBL940668

SCHEMBL940668

O=C(O)c1cccc(-n2cccn2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 2/20 0.59
LMNA P02545 2/20 0.56
HTT P42858 1/20 0.54
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
ALDH1A1 P00352 3/20 0.50
GAA P10253 3/20 0.50
KDM4E B2RXH2 2/20 0.50
HSD17B10 Q99714 2/20 0.50
HPGD P15428 2/20 0.50
MAPT P10636 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
USP2 O75604 1/20 0.50
MYC P01106 1/20 0.50
POLB P06746 1/20 0.50
HSPA1A P0DMV8 1/20 0.50
ALOX15 P16050 1/20 0.50
NR4A1 P22736 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29488339 1.00 KAT6A (0.59) KAT6ALMNAHTTMEN1KMT2A
SCHEMBL5929327 0.88 KAT6A (0.56) KAT6ALMNAMEN1KMT2AALDH1A1
SCHEMBL2161445 0.87 LMNA (0.56) KAT6ALMNAKMT2AALDH1A1GAA
SCHEMBL31173853 0.87 LMNA (0.56) KAT6ALMNAKMT2AALDH1A1GAA
SCHEMBL9807573 0.85 KAT6A (0.54) KAT6ALMNAMEN1KMT2AALDH1A1
SCHEMBL27273126 0.85 KAT6A (0.54) KAT6ALMNAMEN1KMT2AALDH1A1
SCHEMBL16220632 0.85 KAT6A (0.54) KAT6ALMNAMEN1KMT2AALDH1A1
SCHEMBL6607286 0.83 LMNA (0.64) KAT6ALMNAHTTKMT2AALDH1A1
SCHEMBL1645251 0.83 LMNA (0.52) KAT6ALMNAHTTALDH1A1KDM4E
SCHEMBL27931328 0.83 ELANE (0.56) KAT6ALMNAKMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0836593-B1 5-PYRAZOLYLBENZOIC ACID DERIVATIVES AS HERBICIDES BASF AG (DE) 2001-02-14 EP claimed
US-6096689-A AND FOR DESICCATING OR DEFOLIATING PLANTS; APPLYING TO CROPS, IN PARTICULAR, COTTON BASF AKTIENGESELLSCHAFT (DE) 2000-08-01 US claimed
CN-1190392-A 5-pyrazolylbenzoic acid derivatives as herbicides BASF AG (DE) 1998-08-12 CN claimed
US-5039329-A Plant growth regulators CIBA-GEIGY CORPORATION (US) 1991-08-13 US claimed
US-4946492-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1990-08-07 US claimed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 EP disclosed
EP-4676929-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2026-01-14 EP disclosed
US-12492193-B2 Pyrazole derivatives for the treatment of cystic fibrosis FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) 2025-12-09 US disclosed
EP-4638447-A1 IMIDAZO[1,2-A]PYRIDINE AND IMIDAZO[1,2-A]PYRAZINE DERIVATIVES AS MLLT1 AND MLLT3 INHIBITORS Dark Blue Therapeutics Ltd (GB) 2025-10-29 EP disclosed
EP-4626871-A1 CD93 INHIBITORS Universität Bern (CH) 2025-10-08 EP disclosed
US-20240327410-A1 Monoacylglycerol Lipase Modulators JANSSEN PHARMACEUTICA NV (BE) 2024-10-03 US disclosed
WO-2024188906-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2024-09-19 WO disclosed
CN-1190392-A 5-pyrazolylbenzoic acid derivatives as herbicides BASF AG (DE) 1998-08-12 CN disclosed
EP-0836593-A1 5-PYRAZOLYLBENZOIC ACID DERIVATIVES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-04-22 EP disclosed
WO-1997002251-A1 5-PYRAZOLYLBENZOIC ACID DERIVATIVES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-01-23 WO disclosed
US-5039329-A Plant growth regulators CIBA-GEIGY CORPORATION (US) 1991-08-13 US disclosed
US-5039329-A Plant growth regulators CIBA-GEIGY CORPORATION (US) 1991-08-13 US disclosed
US-4946492-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1990-08-07 US disclosed
US-4946492-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1990-08-07 US disclosed
EP-0347382-A2 5-(Pyrazol-1-yl) benzoic acid thiolesters having herbicide activity CIBA-GEIGY AG (CH) 1989-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492193-B2 Pyrazole derivatives for the treatment of cystic fibrosis CFTR, ABCC5, ABCC1 KAT6A 3237/4885LMNA 4394/4885HTT 4543/4885
US-20240327410-A1 Monoacylglycerol Lipase Modulators MGLL, LPL, PNLIP KAT6A 547/4885LMNA 1845/4885HTT 3309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.