Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27121468 | 0.94 | KMT2A (0.39) | NR1H2NR1H3KMT2ATSHRKDM4E | |
| SCHEMBL26848593 | 0.82 | KDM4E (0.41) | NR1H2NR1H3KMT2ATSHRKDM4E | |
| SCHEMBL8695092 | 0.79 | KDM4E (0.52) | KMT2AKDM4EPKMMEN1GPR119 | |
| SCHEMBL24700258 | 0.77 | NR1H2 (0.57) | NR1H2NR1H3KMT2ATSHRMAPT | |
| SCHEMBL27273682 | 0.76 | ACKR3 (0.45) | KDM4EPKMRORCUSP30 | |
| SCHEMBL3714607 | 0.75 | MEN1 (0.50) | KMT2AKDM4EPKMMEN1GPR119 | |
| SCHEMBL14813528 | 0.74 | ALDH1A1 (0.45) | NR1H2NR1H3KMT2ATSHRALDH1A1 | |
| SCHEMBL25811526 | 0.73 | USP30 (0.39) | KMT2ATSHRKDM4EPKMMAPT | |
| SCHEMBL21345451 | 0.72 | KDM4E (0.43) | NR1H2NR1H3KMT2ATSHRKDM4E | |
| SCHEMBL24982513 | 0.72 | KDM4E (0.41) | NR1H2NR1H3KMT2AKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112692-A1 | CASITAS B-LINEAGE LYMPHOMA PROTOONCOGENE B (CBL-B) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |