Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | TRHR | P34981 | 1/20 | 0.46 |
| ▸ | NLN | Q9BYT8 | 4/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26625862 | 0.86 | DPP4 (0.71) | DPP4DPP7CYP3A4SLC7A5TRHR | |
| SCHEMBL27210419 | 0.86 | DPP4 (0.71) | DPP4DPP7CYP3A4SLC7A5TRHR | |
| SCHEMBL30477930 | 0.86 | DPP4 (0.71) | DPP4DPP7CYP3A4SLC7A5TRHR | |
| SCHEMBL30839655 | 0.76 | DPP4 (0.66) | DPP4DPP7CYP3A4SLC7A5TRHR | |
| SCHEMBL27913326 | 0.75 | CYP3A4 (0.69) | CYP3A4SLC7A5NLN | |
| SCHEMBL24668850 | 0.75 | DPP4 (0.43) | DPP4DPP7CYP3A4SLC7A5TRHR | |
| SCHEMBL31649037 | 0.73 | DPP4 (0.71) | DPP4DPP7CYP3A4SLC7A5TRHR | |
| SCHEMBL27776880 | 0.73 | CYP3A4 (0.57) | DPP4CYP3A4SLC7A5NLN | |
| SCHEMBL27273945 | 0.72 | CYP3A4 (0.50) | DPP4CYP3A4SLC7A5NLNREN | |
| SCHEMBL27484466 | 0.72 | DPP4 (0.69) | DPP4DPP7CYP3A4SLC7A5TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1020457-C | Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof | TANABE SEIYAKU CO (JP) | 1993-05-05 | — | — | CN | disclosed |
| CN-85105655-A | Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof | — | 1987-01-28 | — | — | CN | disclosed |