SCHEMBL27274451

SCHEMBL27274451

c1ccc(-c2ccc3ccc(-c4ccc5cc(N(c6ccccc6)c6ccc(-c7cccc8oc9ccccc9c78)cc6)ccc5c4)cc3c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
PGR P06401 1/20 0.35
PLA2G2A P14555 3/20 0.34
PLA2G4A P47712 3/20 0.34
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
HCRTR1 O43613 1/20 0.33
BACE1 P56817 1/20 0.33
ANO1 Q5XXA6 1/20 0.33
PLA2G10 O15496 1/20 0.33
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
PRKDC P78527 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
ALOX5 P09917 1/20 0.32
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27274445 0.98 PGR (0.36) ESR1ESR2PGRPLA2G2APLA2G4A
SCHEMBL23225088 0.95 CASP3 (0.36) ESR1ESR2PGRPLA2G2APLA2G4A
SCHEMBL27274455 0.95 CASP3 (0.36) ESR1ESR2PGRPLA2G2APLA2G4A
SCHEMBL23225079 0.95 CASP3 (0.36) ESR1ESR2PGRPLA2G2APLA2G4A
SCHEMBL24918682 0.95 CASP3 (0.36) ESR1ESR2PGRPLA2G2APLA2G4A
SCHEMBL23179721 0.94 PLA2G2A (0.36) ESR1ESR2PGRPLA2G2APLA2G4A
SCHEMBL23179137 0.94 PLA2G2A (0.36) ESR1ESR2PGRPLA2G2APLA2G4A
SCHEMBL23179113 0.94 PLA2G2A (0.36) ESR1ESR2PGRPLA2G2APLA2G4A
SCHEMBL24842879 0.94 PLA2G2A (0.36) ESR1ESR2PGRPLA2G2APLA2G4A
SCHEMBL29303574 0.94 PLA2G2A (0.36) ESR1ESR2PGRPLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024039095-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2024-02-22 WO disclosed