Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | SCN11A | Q9UI33 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20438228 | 0.76 | SMN1; SMN2 (0.42) | CHRM5ADRA2CGBA1ACHESMN1; SMN2 | |
| SCHEMBL13905846 | 0.73 | SMN1; SMN2 (0.47) | CHRM5ADRA2CGBA1ACHESMN1; SMN2 | |
| SCHEMBL13905729 | 0.72 | SMN1; SMN2 (0.50) | CHRM5ADRA2CGBA1ACHESMN1; SMN2 | |
| SCHEMBL23441833 | 0.69 | SCN1A (0.38) | CHRM5ADRA2CGBA1ACHESCN1A | |
| SCHEMBL17873962 | 0.69 | SMN1; SMN2 (0.43) | CHRM5ADRA2CGBA1SMN1; SMN2SCN1A | |
| SCHEMBL10509286 | 0.68 | GBA1 (0.56) | CHRM5ADRA2CGBA1ACHESMN1; SMN2 | |
| SCHEMBL1437686 | 0.67 | — | — | |
| SCHEMBL24256245 | 0.67 | GBA1 (0.60) | CHRM5ADRA2CGBA1ACHESMN1; SMN2 | |
| SCHEMBL24491906 | 0.67 | CHRM5 (0.46) | CHRM5ADRA2CGBA1ACHESMN1; SMN2 | |
| SCHEMBL24491581 | 0.67 | CHRM5 (0.46) | CHRM5ADRA2CGBA1ACHESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024036254-A2 | SYNTHETIC PROCESSES AND INTERMEDIATES FOR PREPARING THERAPEUTIC AZAKETOLIDES | ZIKANI THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |