SCHEMBL27275

SCHEMBL27275

COC(=O)C(OC)c1ccccc1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.44
FGFR1 P11362 1/20 0.43
SRC P12931 1/20 0.43
FGFR2 P21802 1/20 0.43
FGFR4 P22455 1/20 0.43
FGFR3 P22607 1/20 0.43
HTT P42858 2/20 0.42
ALDH1A1 P00352 5/20 0.41
MITF O75030 1/20 0.41
MAPT P10636 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
GAA P10253 2/20 0.39
POLB P06746 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
THRB P10828 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PPARA Q07869 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2393348 0.86 KMT2A (0.43) KMT2AFGFR1SRCFGFR2FGFR4
SCHEMBL15441693 0.84 KMT2A (0.40) KMT2AFGFR1SRCFGFR2FGFR4
SCHEMBL2393788 0.84 GAA (0.41) KMT2AFGFR1SRCFGFR2FGFR4
SCHEMBL2393244 0.83 BCAT2 (0.44) KMT2AFGFR1SRCFGFR2FGFR4
SCHEMBL24469716 0.82 ALDH1A1 (0.50) ALDH1A1GAAPOLBTAS1R3TAS1R1
SCHEMBL30585539 0.82 ALDH1A1 (0.50) ALDH1A1GAAPOLBTAS1R3TAS1R1
SCHEMBL10710439 0.81 KMT2A (0.46) KMT2AFGFR1SRCFGFR2FGFR4
SCHEMBL1901275 0.81 KMT2A (0.46) KMT2AFGFR1SRCFGFR2FGFR4
SCHEMBL2394159 0.81 KMT2A (0.46) KMT2AFGFR1SRCFGFR2FGFR4
SCHEMBL27783679 0.80 KMT2A (0.49) KMT2AFGFR1SRCFGFR2FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024134480-A1 HETEROCYCLIC ACRYLIC ACID DERIVATIVES AS MONOMERS FOR THE SYNTHESIS OF POLYMERS FOR USE IN ION EXCHANGE ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-06-27 WO disclosed
EP-4136070-B1 MONOMERS, POLYMERS, AND ARTICLES FOR BIOMATERIAL CAPTURE SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-05-29 EP disclosed
US-11912801-B2 (Meth)acrylate urethane (urea) phosphonates as adhesion promoters 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-02-27 US disclosed
EP-4240800-A1 CROSSLINKABLE AND CROSSLINKED COMPOSITIONS 3M Innovative Properties Company (US) 2023-09-13 EP disclosed
WO-2023105327-A1 ADHESIVES COMPRISING CYCLIC IMIDE ADDITION-FRAGMENTATION AND ADHESION AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-06-15 WO disclosed
EP-4136070-A1 MONOMERS, POLYMERS, AND ARTICLES FOR BIOMATERIAL CAPTURE 3M Innovative Properties Company (US) 2023-02-22 EP disclosed
WO-2022096967-A1 CROSSLINKABLE AND CROSSLINKED COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-05-12 WO disclosed
WO-2021209859-A1 MONOMERS, POLYMERS, AND ARTICLES FOR BIOMATERIAL CAPTURE 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-10-21 WO disclosed
EP-3844230-A1 (METH)ACRYLATE URETHANE (UREA) PHOSPHONATES AS ADHESION PROMOTERS 3M Innovative Properties Company (US) 2021-07-07 EP disclosed
WO-2021105843-A1 BIOTIN-CONTAINING MONOMERS AND ARTICLES FORMED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-06-03 WO disclosed
WO-2011126742-A1 CROSSLINKABLE SYRUP COPOLYMERS WITH AMINOALKYL (METH)ACRYLOYL SOLVENT MONOMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-10-13 WO disclosed
EP-2374790-A1 BIPHENYLACETAMIDE DERIVATIVE Dainippon Sumitomo Pharma Co., Ltd. (JP) 2011-10-12 EP disclosed
US-20110224304-A1 BIPHENYLACETAMIDE DERIVATIVE DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2011-09-15 US disclosed
WO-2011087664-A1 (METH)ACRYLOYL-AZIRIDINE CROSSLINKING AGENTS AND ADHESIVE POLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-07-21 WO disclosed
WO-2011063070-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINYL-EPOXY CROSSLINKING SYSTEM 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-05-26 WO disclosed
EP-2291478-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS 3M Innovative Properties Company (US) 2011-03-09 EP disclosed
EP-2257577-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS 3M Innovative Properties Company (US) 2010-12-08 EP disclosed
WO-2010104645-A1 AZIRIDINE CROSSLINKING AGENTS FOR ACRYLIC ADHESIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-09-16 WO disclosed
WO-2009152126-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-17 WO disclosed
WO-2009102623-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224304-A1 BIPHENYLACETAMIDE DERIVATIVE HRH3, KCNH3, BRPF3 KMT2A 78/4885FGFR1 294/4885SRC 2996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.