Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780318 | 0.88 | ALPI (0.61) | PPARGPPARAALPIPKMPTGS1 | |
| SCHEMBL1449126 | 0.88 | ALPI (0.61) | PPARGPPARAALPIPKMPTGS1 | |
| SCHEMBL27373982 | 0.88 | ALPI (0.61) | PPARGPPARAALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL6896783 | 0.86 | ALPI (0.59) | PPARGPPARAALPIPKMPTGS1 | |
| SCHEMBL29131645 | 0.86 | ALPI (0.49) | PPARGPPARAKMT2AALPIPKM | |
| SCHEMBL579041 | 0.85 | SLC6A4 (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL20898438 | 0.85 | ALPI (0.51) | PPARGPPARAALPIPKMPTGS1 | |
| Phenylalanine SCHEMBL5699042 | 0.85 | SLC7A5 (0.69) | PPARGPPARAALPIPKMPTGS1 | |
| SCHEMBL1003560 | 0.85 | SLC7A5 (0.69) | PPARGPPARAALPIPKMPTGS1 | |
| Phenylalanine SCHEMBL5608077 | 0.85 | SLC7A5 (0.69) | PPARGPPARAALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1015711-B | Cycloalkaho [1,2-b] indole-sulphonamides | BAYER AG (DE) | 1992-03-04 | — | — | CN | disclosed |
| CN-87100773-A | Cycloalkanes is [1,2-b] indoles-sulfamide compound also | — | 1987-09-02 | — | — | CN | disclosed |