SCHEMBL29131645

SCHEMBL29131645

NCC(=O)c1ccc(OC(=O)[C@@H](N)Cc2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.49
PKM P14618 1/20 0.49
PTGS1 P23219 1/20 0.49
XIAP P98170 1/20 0.49
SLC7A5 Q01650 1/20 0.49
PPARG P37231 3/20 0.44
PPARA Q07869 3/20 0.44
MMP2 P08253 1/20 0.43
SLC15A1 P46059 2/20 0.43
LNPEP Q9UIQ6 3/20 0.42
ELANE P08246 1/20 0.42
STS P08842 1/20 0.42
KMT2A Q03164 1/20 0.42
LTA4H P09960 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
LAP3 P28838 1/20 0.40
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27277366 0.86 PPARG (0.59) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27373982 0.85 ALPI (0.61) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7780318 0.85 ALPI (0.61) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL1449126 0.85 ALPI (0.61) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL6896783 0.84 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL1003560 0.82 SLC7A5 (0.69) ALPIPKMPTGS1XIAPSLC7A5
Phenylalanine SCHEMBL5608077 0.82 SLC7A5 (0.69) ALPIPKMPTGS1XIAPSLC7A5
Phenylalanine SCHEMBL5699042 0.82 SLC7A5 (0.69) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27990659 0.82 PPARG (0.55) ALPIPKMPTGS1XIAPSLC7A5
Ammonia Solution, Strong SCHEMBL4780834 0.81 SLC7A5 (0.67) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117269494-A A group of metabolic markers for breast cancer lung metastasis 厦门大学 2023-12-22 CN disclosed