SCHEMBL27277486

SCHEMBL27277486

SCC1CCC1c1ccc(Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.47
HTR2C P28335 1/20 0.47
HTR2B P41595 1/20 0.47
SLC6A3 Q01959 1/20 0.44
MDM2 Q00987 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20749174 0.80 HTR2A (0.47) HTR2AHTR2CHTR2BSLC6A3
SCHEMBL432520 0.69 PTGIR (0.46)
SCHEMBL17806041 0.68 HTR2A (0.47) HTR2AHTR2CHTR2BSLC6A3MDM2
SCHEMBL16451639 0.68 HTR2A (0.47) HTR2AHTR2CHTR2BSLC6A3MDM2
SCHEMBL4000922 0.68 MDM2 (0.43) HTR2AHTR2CHTR2BSLC6A3MDM2
SCHEMBL19771738 0.68 MDM2 (0.43) HTR2AHTR2CHTR2BSLC6A3MDM2
SCHEMBL15291807 0.68 HTR2A (0.47) HTR2AHTR2CHTR2BSLC6A3MDM2
SCHEMBL15282173 0.68 HTR2A (0.47) HTR2AHTR2CHTR2BSLC6A3MDM2
SCHEMBL21668620 0.68 SLC6A3 (0.48) HTR2AHTR2CHTR2BSLC6A3MDM2
Hydrochloric Acid SCHEMBL16372230 0.67 HTR2A (0.50) HTR2AHTR2CHTR2BSLC6A3MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1012733-B Process for the preparation of therapeutic agents BOOTS CO PLC (GB) 1991-06-05 CN disclosed
CN-86100954-A The preparation method of therapeutical agent and application 1986-09-03 CN disclosed