Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6787058 | 0.78 | PTPN11 (0.48) | PTPN11TXNRD1TXNRD3TXNRD2KDM4E | |
| SCHEMBL6786957 | 0.72 | PTPN11 (0.42) | PTPN11TXNRD1TXNRD3TXNRD2KDM4E | |
| SCHEMBL257286 | 0.72 | PTPN11 (0.48) | PTPN11TXNRD1TXNRD3TXNRD2KDM4E | |
| SCHEMBL15197891 | 0.71 | PIN1 (0.42) | APPKDM4EALDH1A1PIN1GLA | |
| SCHEMBL622637 | 0.71 | CDK5 (0.47) | KDM4EALDH1A1PIN1GLAGAA | |
| SCHEMBL1420076 | 0.70 | KCNJ1 (0.53) | APPKDM4EALDH1A1PIN1GLA | |
| SCHEMBL29498337 | 0.70 | DYRK1A (0.48) | KDM4EALDH1A1PIN1GLAGAA | |
| SCHEMBL29392214 | 0.70 | NQO2 (0.50) | KDM4EALDH1A1PIN1GLAGAA | |
| SCHEMBL1996329 | 0.70 | NQO2 (0.50) | KDM4EALDH1A1PIN1GLAGAA | |
| Methane SCHEMBL28258537 | 0.70 | CDK5 (0.46) | KDM4EALDH1A1PIN1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-20 | — | — | US | disclosed |
| EP-2897183-B1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | RAYNERGY TEK INC (TW) | 2020-04-29 | — | — | EP | disclosed |
| EP-2897183-B1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | RAYNERGY TEK INC (TW) | 2020-04-29 | — | — | EP | disclosed |
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| EP-2828904-B1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | RAYNERGY TEK INC (TW) | 2019-06-12 | — | — | EP | disclosed |
| EP-2828904-B1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | RAYNERGY TEK INC (TW) | 2019-06-12 | — | — | EP | disclosed |
| WO-2013142835-A1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | POLYERA CORPORATION (US) | 2013-09-26 | — | — | WO | disclosed |
| US-20130247990-A1 | Conjugated Polymers and Their Use in Optoelectronic Devices | RAYNERGY TEK INC. (TW) | 2013-09-26 | — | — | US | disclosed |
| US-20130247990-A1 | Conjugated Polymers and Their Use in Optoelectronic Devices | RAYNERGY TEK INC. (TW) | 2013-09-26 | — | — | US | disclosed |
| EP-2630676-A1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | Polyera Corporation (US) | 2013-08-28 | — | — | EP | disclosed |
| US-20130200354-A1 | Conjugated Polymers and Their Use in Optoelectronic Devices | POLYERA CORPORATION (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130200355-A1 | Conjugated Polymers and Their Use in Optoelectronic Devices | POLYERA CORPORATION (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130200355-A1 | Conjugated Polymers and Their Use in Optoelectronic Devices | POLYERA CORPORATION (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130200354-A1 | Conjugated Polymers and Their Use in Optoelectronic Devices | POLYERA CORPORATION (US) | 2013-08-08 | — | — | US | disclosed |
| WO-2012054910-A1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | POLYERA CORPORTION (US) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012054910-A1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | POLYERA CORPORTION (US) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | PTPN11 4087/4885TXNRD1 876/4885TXNRD3 113/4885 |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | PTPN11 4087/4885TXNRD1 876/4885TXNRD3 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.