SCHEMBL27280211

SCHEMBL27280211

Cc1ccc2c(c1)c1c(C)c(C)cc3c4ccccc4c4cccc2c4c31

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 7/20 0.40
CYP2A6 P11509 5/20 0.40
KIF11 P52732 1/20 0.38
MAOA P21397 2/20 0.37
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34
ALDH1A1 P00352 2/20 0.33
ACHE P22303 2/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
THRB P10828 1/20 0.33
MLKL Q8NB16 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
ERBB2 P04626 1/20 0.32
FYN P06241 1/20 0.32
AHR P35869 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8840866 0.77 CYP1A2 (0.50) CYP1A2CYP2A6KIF11MAOAMEN1
SCHEMBL27832989 0.77 CYP1A2 (0.50) CYP1A2CYP2A6KIF11MAOAMEN1
SCHEMBL18462923 0.76 CYP1A2 (0.35) CYP1A2CYP2A6KIF11ALDH1A1HPGD
SCHEMBL31238980 0.75 CYP1A2 (0.48) CYP1A2CYP2A6KIF11MAOAMEN1
SCHEMBL28488893 0.75 CYP1A2 (0.48) CYP1A2CYP2A6KIF11MAOAMEN1
SCHEMBL18462345 0.75 LDHA (0.42) MEN1KMT2ANPC1POLBALDH1A1
SCHEMBL29511317 0.74 ALDH1A1 (0.42) CYP1A2CYP2A6KIF11MEN1KMT2A
SCHEMBL23156698 0.74 ALDH1A1 (0.44) CYP1A2CYP2A6KIF11ALDH1A1HPGD
SCHEMBL17180585 0.73 KIF11 (0.54) CYP1A2CYP2A6KIF11MAOAMEN1
SCHEMBL8840916 0.73 KIF11 (0.54) CYP1A2CYP2A6KIF11MAOAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024128186-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL CURED LAYER, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE 富士フイルム株式会社 2024-06-20 WO disclosed