Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800385 | 0.92 | CYP19A1 (0.51) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL6761969 | 0.86 | CYP19A1 (0.66) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL5049441 | 0.86 | CYP19A1 (0.71) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL27820726 | 0.85 | CYP19A1 (0.71) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL1301606 | 0.85 | CYP19A1 (0.71) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL8908923 | 0.82 | CYP19A1 (0.53) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL29099957 | 0.82 | CYP19A1 (0.53) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL5120138 | 0.81 | CYP19A1 (0.52) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| Toluene SCHEMBL28164691 | 0.80 | CYP19A1 (0.61) | CYP19A1ALDH1A1MAPK1L3MBTL1STS | |
| SCHEMBL13266074 | 0.80 | ALDH1A1 (0.64) | CYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1015361-B | ENANTIOMERIC GLUTARAMIDE DIURETIC AGENTS | PFIZER (US) | 1992-02-05 | — | — | CN | disclosed |
| CN-1037704-A | The glutaramide diuretic agents of enantiomorph | PFIZER (US) | 1989-12-06 | — | — | CN | disclosed |