Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.53 |
| ▸ | HRH1 | P35367 | 5/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761969 | 0.85 | CYP19A1 (0.66) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL5049441 | 0.85 | CYP19A1 (0.71) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL5048395 | 0.84 | CYP19A1 (0.75) | CYP19A1 | |
| SCHEMBL27820726 | 0.83 | CYP19A1 (0.71) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL1301606 | 0.83 | CYP19A1 (0.71) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| Hydrochloric Acid SCHEMBL4072239 | 0.83 | TDP1 (0.50) | HRH1CHRM3GBA1 | |
| SCHEMBL27280787 | 0.82 | CYP19A1 (0.54) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL29099957 | 0.81 | CYP19A1 (0.53) | CYP19A1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL13266074 | 0.78 | ALDH1A1 (0.64) | CYP19A1HRH1CHRM3ALDH1A1 | |
| SCHEMBL3357147 | 0.78 | MGLL (0.52) | CHRM3ALDH1A1MAPK1L3MBTL1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959882-A | Imidazole carbonyl compound | DAIICHI SANKYO CO LTD | 2011-01-26 | — | — | CN | disclosed |
| CN-101454299-A | Ureide derivative and use thereof for medical purposes | TORAY INDUSTRIES (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1150192-C | Piperidines as CCR5 modulators | — | 2004-05-19 | — | — | CN | disclosed |
| CN-1331691-A | Piperidines as CCR5 modulators | PFIZER LTD (US) | 2002-01-16 | — | — | CN | disclosed |
| CN-1183770-A | Piperazine derivatives, medicaments containing these compounds, their use and processes for their preparation | THOMAE GMBH DR K (DE) | 1998-06-03 | — | — | CN | disclosed |
| US-5661148-A | ANTIHYPOXIC AGENT FOR RESPIRATORY SYSTEM DISORDER | TEIJIN LIMITED (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0514540-B1 | PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 1996-07-17 | — | — | EP | disclosed |
| EP-0514540-A1 | PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1992-11-25 | — | — | EP | disclosed |