Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 9/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 9/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 9/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 3/20 | 0.65 |
| ▸ | HTR1D | P28221 | 4/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.62 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.62 |
| ▸ | HTR1B | P28222 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | HRH2 | P25021 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27277154 | 0.91 | ADRA2C (0.56) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL6844110 | 0.86 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL27271490 | 0.82 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| Apraclonidine SCHEMBL34128 | 0.80 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL10414088 | 0.80 | ADRA2A (0.71) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL11180812 | 0.80 | ADRA2A (0.76) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| Bromide SCHEMBL11608848 | 0.79 | ADRA2A (0.69) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| Apraclonidine SCHEMBL1002875 | 0.79 | BLM (1.00) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| Apraclonidine SCHEMBL1649431 | 0.79 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL10748591 | 0.79 | CFB (0.56) | ADRA2AADRA2BADRA2CADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-86108972-A | New benzamides and preparation method thereof and the application in treatment | — | 1987-11-18 | — | — | CN | claimed |
| CN-1018454-B | BENZAMIDES, METHOD OF OBTAINING THEM AND THERAPEUTIC APPLICATIONS | ILE DE FRANCE (FR) | 1992-09-30 | — | — | CN | disclosed |
| CN-86108972-A | New benzamides and preparation method thereof and the application in treatment | — | 1987-11-18 | — | — | CN | disclosed |