SCHEMBL2728161

SCHEMBL2728161

COc1c(F)c(F)c(-c2c3ccccc3c(-c3ccc(F)c(F)c3)c3c(F)c(F)c(F)c(F)c23)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.36
CTNNB1 P35222 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
FABP4 P15090 1/20 0.35
FABP5 Q01469 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PTGS2 P35354 4/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
STAT3 P40763 1/20 0.32
PAX8 Q06710 1/20 0.32
PTGS1 P23219 2/20 0.32
PDGFRB P09619 1/20 0.32
PDGFRA P16234 1/20 0.32
ACLY P53396 1/20 0.30
TUBB4A P04350 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2726467 0.93 BCL9 (0.37) BCL9CTNNB1L3MBTL1FABP4FABP5
SCHEMBL2726648 0.89 KDM4E (0.35) L3MBTL1KDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL2727807 0.89 L3MBTL1 (0.38) BCL9CTNNB1L3MBTL1FABP4FABP5
SCHEMBL2728461 0.89 CYP1A1 (0.35) L3MBTL1KDM4EALDH1A1MAPK1
SCHEMBL2726048 0.88 PARP1 (0.34) BCL9CTNNB1MEN1KMT2AALDH1A1
SCHEMBL2733608 0.88 BCL9 (0.34) BCL9CTNNB1L3MBTL1FABP4FABP5
SCHEMBL2936452 0.87 BCL9 (0.39) BCL9CTNNB1L3MBTL1MEN1KMT2A
SCHEMBL2728890 0.87 BCL9 (0.35) BCL9CTNNB1L3MBTL1FABP4FABP5
SCHEMBL2711263 0.86 L3MBTL1 (0.36) BCL9CTNNB1L3MBTL1FABP4FABP5
SCHEMBL2724358 0.85 ALDH1A1 (0.45) MEN1KMT2AKDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 BCL9 185/4885CTNNB1 965/4885L3MBTL1 2477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.