SCHEMBL2711263

SCHEMBL2711263

COc1c(F)c(F)c(-c2c3ccccc3c(-c3ccc(F)c(F)c3)c3cc(F)c(F)cc23)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.36
FABP4 P15090 1/20 0.36
FABP5 Q01469 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
BCL9 O00512 1/20 0.35
CTNNB1 P35222 1/20 0.35
PTGS2 P35354 4/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
PAX8 Q06710 1/20 0.33
STAT3 P40763 1/20 0.33
PTGS1 P23219 2/20 0.33
PDGFRB P09619 1/20 0.33
PDGFRA P16234 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ACHE P22303 1/20 0.31
ACLY P53396 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2727807 0.97 L3MBTL1 (0.38) L3MBTL1FABP4FABP5KDM4EALDH1A1
SCHEMBL2709236 0.92 TUBB4A (0.37) L3MBTL1FABP4FABP5BCL9CTNNB1
SCHEMBL2709695 0.90 KDM4E (0.36) L3MBTL1FABP4FABP5KDM4EALDH1A1
SCHEMBL2712303 0.89 ALDH1A1 (0.43) L3MBTL1KDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL2712522 0.89 PARP1 (0.36) L3MBTL1ALDH1A1BCL9CTNNB1PTGS2
SCHEMBL2711840 0.88 PDE4B (0.40) KDM4EALDH1A1MAPK1SMN1; SMN2ABCG2
SCHEMBL2943357 0.88 ALDH1A1 (0.42) L3MBTL1KDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL2726467 0.87 BCL9 (0.37) L3MBTL1FABP4FABP5KDM4EALDH1A1
SCHEMBL2712341 0.87 ACHE (0.45) L3MBTL1KDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL2711159 0.87 BCL9 (0.35) L3MBTL1FABP4FABP5ALDH1A1BCL9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 L3MBTL1 2477/4885FABP4 396/4885FABP5 309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.