Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | ITPR3 | Q14573 | 4/20 | 0.32 |
| ▸ | ITPR2 | Q14571 | 1/20 | 0.32 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25572011 | 0.88 | — | — | |
| SCHEMBL25976118 | 0.84 | TLR4 (0.36) | SMPD1 | |
| SCHEMBL17052659 | 0.84 | TLR4 (0.36) | SMPD1 | |
| SCHEMBL13882147 | 0.83 | FBP1 (0.30) | FBP1 | |
| SCHEMBL27282033 | 0.83 | SMPD1 (0.37) | SMPD1ITPR3ITPR2ITPR1FBP1 | |
| SCHEMBL27282036 | 0.79 | SMPD1 (0.35) | SMPD1 | |
| SCHEMBL25553231 | 0.78 | — | — | |
| SCHEMBL17124623 | 0.78 | — | — | |
| SCHEMBL17775028 | 0.78 | — | — | |
| SCHEMBL19078931 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216522-A1 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING FRIEDREICH'S ATAXIA | DYNE THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216522-A1 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING FRIEDREICH'S ATAXIA | MUSK, ATXN2, ATXN10 | SMPD1 2291/4885ITPR3 3253/4885ITPR2 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.