Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 4/20 | 0.33 |
| ▸ | CHUK | O15111 | 4/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23122695 | 0.84 | HPGD (0.38) | ADORA2AADORA1GDAADORA2BPIK3CD | |
| SCHEMBL23122489 | 0.81 | CACNA2D1 (0.33) | ADORA2AADORA1ALDH1A1PDE4APDE4B | |
| SCHEMBL20200121 | 0.71 | AHCY (0.33) | ADORA2AADORA1GDAADORA2BPIK3CD | |
| SCHEMBL23122556 | 0.69 | GDA (0.46) | ADORA2AADORA1GDAADORA2BPIK3CD | |
| SCHEMBL8737256 | 0.68 | IKBKB (0.36) | ADORA2AADORA1GDAADORA2BPIK3CD | |
| SCHEMBL13348729 | 0.67 | CDK1 (0.37) | ADORA2AADORA1IKBKBCHUKCDK2 | |
| SCHEMBL23122432 | 0.67 | CDK1 (0.39) | ADORA2AADORA1GDAADORA2BPIK3CD | |
| SCHEMBL20203177 | 0.66 | PIK3CD (0.37) | ADORA2AADORA1GDAADORA2BPIK3CD | |
| SCHEMBL15339546 | 0.65 | LMNA (0.35) | ADORA2AADORA1GDAADORA2BPIK3CD | |
| SCHEMBL8737240 | 0.65 | LMNA (0.33) | ADORA2AADORA1POLBIKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006559-A1 | MODULATORS OF NLRP3 INFLAMMASOME AND RELATED PRODUCTS AND METHODS | Neumora Therapeutics, Inc. (US) | 2024-01-04 | — | — | WO | disclosed |